Inflammatory Bowel Disease

Various Bits About Inflammatory Bowel Disease

There are two diseases that are included in the term “Inflammatory Bowel Disease” – which are Crohn’s Disease and Ulcerative Colitis.

Blog re: Inflammatory Bowel Disease Maintained by Mayo Clinic

This is a terrific resource:  LINK


The work of Dr. Deanna Gibson of University of British Columbia, Canada, reported online at Gut Microbiota for Health, by reporter Kristina Campbell, July 31/15  LINK

Quotes (IBD = Inflammatory Bowel Disease):

  • She explains, “The first thing I learned was that a high-fat diet doesn’t equal ‘evil’. It really depends on the type of fat that you are eating. A diet rich in olive oil, for example — even though it’s high fat — I found beneficial during colitis.”
  • When compared to the monounsaturated fat (olive oil) diet for those with IBDs, Gibson’s research showed that a diet high in polyunsaturated fats (found in many common supermarket products) was far inferior. “When [they] eat polyunsaturated fats, omega 6 polyunsaturated fats in particular… that diet turns out to be the worst. It’s very pro-inflammatory. It’s the worst for colitis patients.” Meanwhile, a diet with mostly saturated fats fell somewhere in the middle.
  • “I think probiotics have the potential to be really powerful [for IBDs] because they certainly do have beneficial properties, but clinical trials have been pretty disappointing,” she says. “Probably one of the reasons is because probiotics die in a hostile environment like one found in an IBD gut or somebody with disease: inflammation and [an] oxidized environment. They don’t really know how to compete with the native flora, so they don’t have the right colonization factors.”
  • From Gibson’s point of view, the most promising future strategy for modifying the microbiota in IBD is to use a more sophisticated method of fecal microbiota transplantation. “People are starting to figure out what’s inside the feces that’s important,” she says. “[We will deliver them as] probiotics, but ‘second generation probiotics’, if you will: something that’s a bit more intellectually designed [and] very specific.”

Lee D, Albenberg L, et al. (2015) Diet in the pathogenesis and treatment of inflammatory bowel diseases. Gastroenterology DOI:

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